Prion Disease Testing
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Transmissible spongiform encephalopathies, TSEs.
Testing for prion diseases may be considered for patients with undiagnosed, rapidly progressive dementia.
Information is collected from a variety of sources that may include brain or tonsillar biopsy, cerebrospinal fluid (CSF). Analysis for the presence of 14-3-3 type protein, electroencephalogram (EEG), brain magnetic resonance imaging (MRI), neurologic exams, and patient history.
(Negative biopsy, normal CSF protein levels, normal EEG, normal MRI, normal neurologic examination.