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Common Use:
To assist in diagnosing bacterial infection and risk for developing sepsis.

Serum collected in a gold-, red-, or red/gray-top tube. Plasma collected in a lavender-top (EDTA) or a green-top (lithium or sodium heparin) tube is also acceptable.

Normal Findings:
(Method: Fluorescence immunoassay)

AgeConventional UnitsSI Units (Conventional Units × 1)
NewbornLess than 2 ng/mLLess than 2 mcg/L
18–20 hrLess than 20 ng/mLLess than 20 mcg/L
48 hrLess than 5 ng/mLLess than 5 mcg/L
3 d–adultLess than 0.1 ng/mLLess than 0.1 mcg/L
Interpretive Guidelines
InterpretationConventional UnitsSI Units
Bacterial infection absent or very unlikelyLess than 0.1 ng/mLLess than 0.1 mcg/L
Bacterial infection possible; low risk for development of sepsisLess than 0.5 ng/mLLess than 0.5 mcg/L
Bacterial infection likely; development of sepsis is possible0.5–2 ng/mL0.5–2 mcg/L
Bacterial infection very likely; high risk for development of sepsis2.1–9.9 ng/mL or greater2.1–9.9 mcg/L or greater
Bacterial infection severe; septic shock is probable10 ng/mL or greater10 mcg/L or greater

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