Davis's Lab & Diagnostic Tests

Antidiuretic Hormone

Antidiuretic Hormone is a topic covered in the Davis's Lab & Diagnostic Tests.

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Vasopressin, arginine vasopressin hormone, ADH.

Common Use:
To evaluate disorders that affect urine concentration related to fluctuations of ADH secretion, such as diabetes insipidus.

Plasma collected in a lavender-top (EDTA) tube.

Normal Findings:
(Method: Radioimmunoassay)

AgeAntidiuretic Hormone*SI Units (Conventional Units × 0.923)
NeonatesLess than 1.5 pg/mLLess than 1.4 pmol/L
1 day–18 yr (normally hydrated)0.5–1.7 pg/mLLess than 0.5–1.6 pmol/L
Adult (normally hydrated)1–5 pg/mL0.9–4.6 pmol/L
*Conventional units.


This test should be ordered and interpreted with results of a serum osmolality.

Serum Osmolality*Antidiuretic HormoneSI Units (Conventional Units × 0.923)
270–280 mOsm/kgLess than 1.5 pg/mLLess than 1.4 pmol/L
280–285 mOsm/kgLess than 2.5 pg/mLLess than 2.3 pmol/L
285–290 mOsm/kg1–5 pg/mL0.9–4.6 pmol/L
290–295 mOsm/kg2–7 pg/mL1.8–6.5 pmol/L
295–300 mOsm/kg4–12 pg/mL3.7–11.1 pmol/L
*Conventional units.

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