Bilirubin and Bilirubin Fractions
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Conjugated/direct bilirubin, unconjugated/indirect bilirubin, delta bilirubin, TBil.
A multipurpose laboratory test that acts as an indicator for various diseases of the liver, for disease that affects the liver, or conditions associated with red blood cell (RBC) hemolysis.
Serum collected in gold-, red-, or red/gray-top tube. Plasma collected in green-top (heparin) tube or in a heparinized Microtainer is also acceptable. Protect sample from direct light.
(Method: Spectrophotometry) Total bilirubin levels in infants should decrease to adult levels by day 10 as the development of the hepatic circulatory system matures. Values in breastfed infants may take longer to reach normal adult levels. Values in premature infants may initially be higher than in full-term infants and also take longer to decrease to normal levels.
|Age||Conventional Units||SI Units (Conventional Units × 17.1)|
|Newborn–1 d||Less than 5.8 mg/dL||Less than 99 micromol/L|
|1–2 d||Less than 8.2 mg/dL||Less than 140 micromol/L|
|3–5 d||Less than 11.7 mg/dL||Less than 200 micromol/L|
|6–7 d||Less than 8.4 mg/dL||Less than 144 micromol/L|
|8–9 d||Less than 6.5 mg/dL||Less than 111 micromol/L|
|10–11 d||Less than 4.6 mg/dL||Less than 79 micromol/L|
|12–13 d||Less than 2.7 mg/dL||Less than 46 micromol/L|
|14–30 d||Less than 0.8 mg/dL||Less than 14 micromol/L|
|1 mo–older adult||Less than 1.2 mg/dL||Less than 21 micromol/L|
|Unconjugated bilirubin||Less than 1.1 mg/dL||Less than 19 micromol/L|
|Neonate||Less than 0.6 mg/dL||Less than 10 micromol/L|
|29 d–older adult||Less than 0.3 mg/dL||Less than 5 micromol/L|
|Delta bilirubin||Less than 0.2 mg/dL||Less than 3 micromol/L|