Davis's Lab & Diagnostic Tests

Lipoprotein Electrophoresis

Lipoprotein Electrophoresis is a topic covered in the Davis's Lab & Diagnostic Tests.

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Lipid fractionation; lipoprotein phenotyping; 3ga1-lipoprotein cholesterol, high-density lipoprotein (HDL); β-lipoprotein cholesterol, low-density lipoprotein (LDL); pre-β-lipoprotein cholesterol, very-low-density lipoprotein (VLDL).

Common Use:
To assist in categorizing lipoprotein as an indicator of cardiac health.

Serum collected in a gold-, red-, or red/gray-top tube.

Normal Findings:
(Method: Electrophoresis and 4°C test for specimen appearance) There is no quantitative interpretation of this test. The specimen appearance and electrophoretic pattern is visually interpreted.

Hyperlipoproteinemia: Fredrickson TypeSpecimen AppearanceElectrophoretic Pattern
Type IClear with creamy top layerHeavy chylomicron band
Type IIaClearHeavy β band
Type IIbClear or faintly turbidHeavy β and pre-β bands
Type IIISlightly to moderately turbidHeavy β band
Type IVSlightly to moderately turbidHeavy pre-β band
Type VSlightly to moderately turbid with creamy top layerIntense chylomicron band and heavy β and pre-β bands

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