Davis's Lab & Diagnostic Tests

CD4/CD8 Enumeration and Viral Load Testing

CD4/CD8 Enumeration and Viral Load Testing is a topic covered in the Davis's Lab & Diagnostic Tests.

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T-cell profile.

Common Use:
To monitor HIV disease progression and the effectiveness of retroviral therapy.

Whole blood collected in a green-top (heparin) tube.

Normal Findings:
(Method: Flow cytometry)

Mature T cells (CD3)Helper T cells (CD4)Suppressor T cells (CD8)
AgeAbsolute (cells/microL)%Absolute (cells/microL)%Absolute (cells/microL)%
0–3 mo2,500–5,50053–841,600–4,00035–64560–1,70012–28
3–6 mo2,500–5,60051–771,800–4,00035–56590–1,60012–23
6–12 mo1,900–5,90049–761,400–4,30031–56500–1,70012–24
12–24 mo2,100–6,20053–751,300–3,40032–51620–2,00014–30
2–56 yr1,400–3,70056–75700–2,20028–47490–1,30016–30
6–12 yr1,200–2,60060–76650–1,50031–47370–1,10018–35
12–18 yr1,000–2,20056–84530–1,30031–52330–92018–35
Pediatric values adapted with permission by Elsevier from Shearer, W., et al. (November 2003). Lymphocyte subsets in healthy children from birth through 18 years of age: The pediatric AIDS clinical trials group P1009 study. Journal of Allergy and Clinical Immunology, 112(5): 973–980.

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