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Coproporphyrin, porphobilinogen, urobilinogen, and other porphyrins.

Common Use:
To assess for porphyrins in the urine to assist with diagnosis of genetic disorders associated with porphyrin synthesis as well as heavy metal toxicity.

Urine from a random or timed specimen collected in a clean, amber-colored plastic collection container with sodium carbonate as a preservative.

Normal Findings:
(Method: High-performance liquid chromatography for porphyrins; spectrophotometry for δ-aminolevulinic acid and porphobilinogen)

TestConventional UnitsSI Units
(Conventional units × 1.53)
Coproporphyrin I0–24 mcg/24 h0–36.7 nmol/24 hr
Coproporphyrin III0–74 mcg/24 hr0–113.2 nmol/24 hr
(Conventional units × 1.43)
Uroporphyrins0–24 mcg/24 hr0–34.3 nmol/24 hr
(Conventional units × 1.34)
HexacarboxylporphyrinLess than 1 mcg/24 hrLess than 1.34 nmol/24 hr
(Conventional units × 1.27)
HeptacarboxylporphyrinLess than 4 mcg/24 hrLess than 5.1 nmol/24 hr
(Conventional units × 4.42)
PorphobilinogenLess than 2 mg/24 hrLess than 8.8 micromol/24 hr
(Conventional units × 7.626)
δ-Aminolevulinic acid1.5–7.5 mg/24 hr11.4–57.2 micromol/24 hr

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