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Albumin, urine.

Common Use:
To assist in the identification and management of early diabetes in order to avoid or delay onset of diabetic associated kidney disease.

Urine from a random or timed specimen collected in a clean plastic collection container.

Normal Findings:
(Method: Immunoassay)

TestConventional UnitsSI Units (Conventional Units × .001)
24-hr microalbumin to creatinine ratioLess than 30 mg/g creatinine/24 hrLess than 0.03 mg/g creatinine/24 hr
24-hr microalbumin
 NormalLess than 30 mg/24 hrLess than 0.03 mg/24 hr
 Microalbuminuria30–299 mg/24 hr0.03–0.3 mg/24 hr
 Clinical albuminuria300 mg or greater/24 hr0.3 mg or greater/24 hr
Simultaneous measurement of urine creatinine (Cr) or Cr clearance is usually requested. The American Diabetes Association (ADA) recommends annual measurement of serum Cr and estimated glomerular filtration rate (eGFR) regardless of microalbumin levels; numerous factors such as hydration status, the presence of an infection, or significant hyperglycemia can produce falsely increased or decreased microalbumin levels. Therefore, the ADA recommends classification of microalbuminuria after two of three 24-hr samples collected in a 3- to 6-mo period reflect abnormal results. The National Kidney Foundation defines microalbuminuria as equal to or greater than 30 mg/g Cr/24 hr based on eGFR measurements.

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