Davis's Lab & Diagnostic Tests

Alkaline Phosphatase and Isoenzymes

Alkaline Phosphatase and Isoenzymes was found in Davis's Lab & Diagnostic Tests which delivers information on how the test works, how to accurately interpret results, and how to provide the best care to your patients before, during, and after a test.

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Davis's Lab and Diagnostic Tests

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General

Synonym/Acronym:
Alk Phos, ALP and fractionation, heat-stabile ALP.

Common Use:
To assist in the diagnosis of liver cancer and cirrhosis, or bone cancer and bone fracture.

Specimen:
Serum (1 mL) collected in a red- or tiger-top tube. Plasma (1 mL) collected in a green-top (heparin) tube is also acceptable.

Normal Findings:
(Method: Spectrophotometry for total alkaline phosphatase, inhibition/electrophoresis for fractionation)

Total ALPConventional & SI UnitsBone FractionLiver Fraction
0–30 d
 Male75–375 units/L
 Female65–350 units/L
1–11 mo
 Male70–350 units/L
 Female80–330 units/L
1–5 yr
 Male56–350 units/L39–308 units/LLess than 8–101 units/L
 Female73–378 units/L56–300 units/LLess than 8–53 units/L
6–7 yr
 Male70–364 units/L50–319 units/LLess than 8–76 units/L
 Female73–378 units/L56–300 units/LLess than 8–53 units/L
8 yr
 Male70–364 units/L50–258 units/LLess than 8–62 units/L
 Female98–448 units/L78–353 units/LLess than 8–62 units/L
9–12 yr
 Male112–476 units/L78–339 units/LLess than 8–81 units/L
 Female98–448 units/L78–353 units/LLess than 8–62 units/L
13 yr
 Male112–476 units/L78–389 units/LLess than 8–48 units/L
 Female56–350 units/L28–252 units/LLess than 8–50 units/L
14 yr
 Male112–476 units/L78–389 units/LLess than 8–48 units/L
 Female56–266 units/L31–190 units/LLess than 8–48 units/L
15 yr
 Male70–378 units/L48–311 units/LLess than 8–39 units/L
 Female42–168 units/L20–115 units/LLess than 8–53 units/L
16 yr
 Male70–378 units/L48–311 units/LLess than 8–39 units/L
 Female28–126 units/L14–87 units/LLess than 8–50 units/L
17 yr
 Male56–238 units/L34–190 units/LLess than 8–39 units/L
 Female28–126 units/L17–84 units/LLess than 8–53 units/L
18 yr
 Male56–182 units/L34–146 units/LLess than 8–39 units/L
 Female28–126 units/L17–84 units/LLess than 8–53 units/L
19 yr
 Male42–154 units/L25–123 units/LLess than 8–39 units/L
 Female28–126 units/L17–84 units/LLess than 8–53 units/L
20 yr
 Male45–138 units/L25–73 units/LLess than 8–48 units/L
 Female33–118 units/L17–56 units/LLess than 8–50 units/L
21 yr and older
 Male35–142 units/L11–73 units/L0–93 units/L
 Female25–125 units/L11–73 units/L0–93 units/L
Values may be slightly elevated in older adults.

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